What is the key reactant in the cytochrome P450 catalytic cycle and how is it formed?

Question

Quizplus · Accepted Answer

The Answer is It is the doubly reduced oxygen which may be represented by the short-lived perferryl oxygen intermediate or the phorphyrin radical species. This is produced by a two electron reduction of the heme iron CYPs by cytochrome P450 reductase and transfer to the bound oxygen. The binding of the substrate to the heme iron precedes these reaction steps and leads to an oxidized substrate and the other oxygen forming water.

What Is the Key Reactant in the Cytochrome P450 Catalytic