Hydroxylation is a posttranslational modification that
A) Requires ascorbic acid
B) Is catalyzed by several mixed function oxidases
C) Is required for the structural integrity of globin
D) Both A and B are correct
E) All of the above are correct

Question

Hydroxylation is a posttranslational modification that 
A) Requires ascorbic acid
B) Is catalyzed by several mixed function oxidases
C) Is required for the structural integrity of globin
D) Both A and B are correct
E) All of the above are correct

Quizplus · Accepted Answer

Hydroxylation is a posttranslational modification that requires ascorbic acid (vitamin C) for the activity of prolyl and lysyl hydroxylase enzymes, and is catalyzed by several mixed function oxidases, making both A and B correct. It is crucial for the structural integrity and function of collagen, not globin.

Hydroxylation Is a Posttranslational Modification That