During synthesis of secreted proteins, binding of the ribosome to the ER membrane is mediated by

Question

Quizplus · Accepted Answer

The binding of the ribosome to the ER membrane during the synthesis of secreted proteins is mediated by the Signal Recognition Particle (SRP) and the SRP receptor protein. SRP recognizes the signal sequence of the nascent polypeptide emerging from the ribosome and directs the ribosome to the ER membrane by interacting with its receptor.

During Synthesis of Secreted Proteins, Binding of the Ribosome to the ER