The screening test for cystic fibrosis, which measures an enzyme in the blood, yields many false negatives.

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The screening test for cystic fibrosis typically measures levels of immunoreactive trypsinogen (IRT) in the blood, which is a newborn screening test, and it is not known for yielding many false negatives. Instead, it can have false positives, leading to further testing to confirm a diagnosis.

The Screening Test for Cystic Fibrosis, Which Measures an Enzyme