Which of the following best defines lead-time bias?
A) The screening test looks better than it actually is because younger, healthier people are more likely to get the test.
B) Screening identifies an illness that would not have shown clinical signs before death from other causes.
C) Slow-progressing cases of disease with a better prognosis are more likely to be identified than faster-progressing cases of disease with a poorer prognosis. Thus, cases diagnosed through screening tend to have a better prognosis than the average of all cases.
D) Difference in the time between the date of diagnosis with screening and the date of diagnosis without screening, which, if counted in the survival time of patients, will give a misleading picture of the benefits of treatment
Correct Answer:
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