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How Did Two Graduate Students Discover That the Bursa of Fabricus

Question 52

Multiple Choice

How did two graduate students discover that the bursa of Fabricus (BF) is what produces the cells necessary for antibody-mediated immunity in chickens?


A) The BF was removed from chickens for another study, and when those chickens were injected with bacteria, it turned out they produced no antibodies which meant they were producing no B cells.
B) The BF was removed from chickens for another study and when they were injected with bacteria, it turned out they produced no antibodies which meant they were producing no T cells.
C) They observed that the BF grew rapidly in the weeks after chicks hatched, which would be just when an immune system would be developing.
D) They noticed that chicks without a thymus had no cell-mediated immunity.
E) Some of the chicks without a BF died when injected with bacteria, suggesting they had no effective immune system.

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