Tumors Can Deprive Cells of Oxygen

Tumors can deprive cells of oxygen. This happens through angiogenesis, which is

A) When tumors block the blood stream, preventing oxygen from getting to some of the cells "downstream" from the blockage
B) When tumors cause blood vessels from the circulatory system to grow into the tumor, preventing oxygen and nutrients from traveling to other cells
C) When tumors secrete chemicals that convert oxygen to carbon dioxide, which other cells can't use
D) When tumors lodge in the lungs, blocking oxygen uptake
E) When tumors grow so fast they force the heart to slow down, slowing the transport of oxygen through the body