How Do Signal Molecules Work in a Cancerous Cell

How do signal molecules work in a cancerous cell?

A) They don't usually work at all.
B) Cancer cells interpret them backwards such that growth signals stop growth and growth inhibitors cause growth.
C) Cancer cells make their own signal molecules, are insensitive to them, or simply grow without them.
D) Cancer cells can never interpret signal molecules correctly.
E) Cancer cells use signal molecules just the way normal cells do.