Sickle cell hemoglobin, HbS, doesn't have the same shape as normal hemoglobin, HbA, so it can't bind to the necessary four oxygen molecules. True or False?

Question

Quizplus · Accepted Answer

Sickle cell hemoglobin, HbS, can still bind to four oxygen molecules like normal hemoglobin, HbA. The primary issue with HbS is its tendency to polymerize under low oxygen conditions, causing red blood cells to sickle and impairing their function and circulation.

Sickle Cell Hemoglobin, HbS, Doesn't Have the Same Shape as Normal