In 5$\alpha$-reductase deficiency, males fail to convert testosterone into the potent steroid _______, resulting in _______.

Question

Quizplus · Accepted Answer

5α-Reductase deficiency leads to an inability to convert testosterone into dihydrotestosterone (DHT), which is crucial for the development of male external genitalia. Affected males may present with feminine genitalia until puberty, when increased testosterone levels cause masculinization.

In 5 α\alphaα -Reductase Deficiency, Males Fail to Convert Testosterone into the Potent

In 5 $\alpha$ -Reductase Deficiency, Males Fail to Convert Testosterone into the Potent