A key event that triggers puberty is an increase in GnRH secretion by the hypothalamus, which subsequently activates gonadotropin secretion. Precocious (early-onset) puberty is often treated by manipulating this hormonal system with
A) pulsatile administration of LH and FSH analogs.
B) pulsatile administration of GnRH analogs.
C) administration of LH and FSH analogs at constant high levels.
D) administration of GnRH analogs at constant high levels.
E) administration of high doses of estrogen to reduce GnRH levels through feedback inhibition.
Correct Answer:
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