Prior to Birth, the Ovaries Produce _______ Quantities of Estrogen

Prior to birth, the ovaries produce _______ quantities of estrogen, and external estrogens _______.

A) insignificant; have direct access to the fetal brain
B) insignificant; are prevented from reaching the fetal brain
C) substantial; have direct access to the fetal and maternal brain
D) substantial; are prevented from reaching the fetal brain
E) insignificant; are minimal