Jamie is eight years old and has testes that are undescended and genitals that resemble that of a female. Which disorder of sexual development does Jamie most likely have?

Question

Quizplus · Accepted Answer

5-alpha-reductase deficiency is a condition that affects male sexual development before birth and during puberty. Boys with this condition are genetically male, with one X and one Y chromosome in each cell, and they have testes. However, they lack enough of a hormone called dihydrotestosterone (DHT), which is critical for male genital development. As a result, they may be born with ambiguous genitalia or genitalia that appear more female than male. This condition does not affect the development of male internal reproductive organs (testes). The testes may not descend normally, and at puberty, affected individuals develop more typically male secondary sexual characteristics.

Jamie Is Eight Years Old and Has Testes That Are