A classic organic brain damage syndrome due to chronic alcohol use and deficiency of thiamine (vitamin B₁) is ___________________, which is characterized by confusion, ataxia (lack of coordination of muscle movements, especially while walking), nystagmus (involuntary eye movements), ophthalmoplegia (paralysis or weakness of one or more of the muscles that control eye movement), and peripheral neuropathy (pain in nerves, loss of sensation, and an inability to control muscles).

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Wernicke's encephalopathy is a classic syndrome caused by thiamine deficiency, often due to chronic alcohol use, and is characterized by confusion, ataxia, nystagmus, ophthalmoplegia, and peripheral neuropathy.

A Classic Organic Brain Damage Syndrome Due to Chronic Alcohol