The pharmacological actions of imipramine support _____________.

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Imipramine, a tricyclic antidepressant, primarily works by inhibiting the reuptake of norepinephrine and serotonin, thereby increasing their levels in the synaptic cleft. This action supports the monoamine hypothesis of depression, which suggests that a deficiency in certain neurotransmitters (such as serotonin and norepinephrine) is linked to the pathophysiology of depression.

The Pharmacological Actions of Imipramine Support _____________