Cognitive therapy for depression may facilitate adaptive ________ changes via the PFC while antidepressants may promote a ________ therapeutic approach via the limbic system.

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Cognitive therapy often involves changing thought patterns, which is a top-down process starting from the prefrontal cortex (PFC), influencing emotions and behaviors. Antidepressants primarily affect the limbic system, which is involved in mood regulation, thus promoting a bottom-up approach to therapy by altering brain chemistry and its effects on cognition and behavior.

Cognitive Therapy for Depression May Facilitate Adaptive ________ Changes Via