Which best describes the term used when high frequency pulses delivered at the presynaptic area give rise to a response of potentiation at that synapse but depression at other synapses nearby?

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Heterosynaptic LTD (Long-Term Depression) refers to the phenomenon where a high frequency stimulation of one synapse leads to a decrease in the effectiveness of nearby synapses, contrasting with the potentiation (increase in synaptic strength) at the directly stimulated synapse. This is due to the synaptic plasticity mechanisms that allow neurons to adjust their connections based on activity.

Which Best Describes the Term Used When High Frequency Pulses