Which is both necessary and sufficient to trigger chemical transmitter release from a presynaptic nerve terminal?

Question

Quizplus · Accepted Answer

An increase in presynaptic calcium concentration is both necessary and sufficient for the release of neurotransmitters from a presynaptic nerve terminal. When action potentials reach the nerve terminal, they trigger the opening of voltage-gated calcium channels, allowing calcium to enter the cell. This influx of calcium is the key signal that prompts vesicles containing neurotransmitters to fuse with the presynaptic membrane and release their contents into the synaptic cleft.

Which Is Both Necessary and Sufficient to Trigger Chemical Transmitter