What would happen to metabotropic signaling in a cell if you added GTP-γ-s to the cell cytoplasm?
A) This would irreversibly activate all G protein-coupled metabotropic signaling.
B) This would irreversibly inhibit all G protein-coupled metabotropic signaling.
C) This would have no effect on G protein-coupled metabotropic signaling.
D) This would irreversibly activate G protein-coupled metabotropic signaling mediated by only Gi and Go.
E) This would irreversibly inhibit G protein-coupled metabotropic signaling mediated by only Gi and Go.
Correct Answer:
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