How Do Transmitters Act on the Postsynaptic Cell at Direct

How do transmitters act on the postsynaptic cell at direct chemical synapses?

A) They diffuse across postsynaptic membranes to excite postsynaptic cells.
B) They bind to voltage-gated ion channels to induce postsynaptic current flux.
C) They bind to metabotropic receptors to induce postsynaptic biochemical changes.
D) They bind to ligand-gated ion channels to induce postsynaptic current flux.
E) They bind to extracellular matrix molecules to excite postsynaptic cells.