Under which of the following conditions would you expect NMDA receptors to contribute to postsynaptic currents in the hippocampus?

Question

Quizplus · Accepted Answer

NMDA receptors require a depolarization of the postsynaptic membrane to relieve the Mg2+ block and allow current flow. A train of presynaptic action potentials at high frequency is more likely to sufficiently depolarize the postsynaptic neuron, allowing NMDA receptors to contribute to postsynaptic currents.

Under Which of the Following Conditions Would You Expect NMDA