Desensitization therapy works by

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Quizplus · Accepted Answer

Desensitization therapy works by several mechanisms to reduce allergic responses. These include producing IgG antibodies that compete with IgE for antigen binding sites, thereby preventing the activation of mast cells and basophils. IgG can also activate inhibitory Fc receptors (ITIMs) on cells, which helps to downregulate the allergic response. Additionally, desensitization can lead to a shift in the immune response from a Th2 (associated with allergic responses) to a Th1 profile, which is more about fighting infections and less about promoting allergies. It can also induce anergy in Th2 cells, making them less responsive to allergens.

Desensitization Therapy Works by