Which of the following is a way in which follicular B cells can acquire antigen entering a lymph node via an afferent lymphatic?
A) Direct capture of whole antigen that directly enters the follicle by passing between subcapsular sinus macrophages.
B) Transfer of complement-bound antigen from surface receptors on subcapsular sinus macrophages to B cells.
C) Passage of antigen from subcapsular sinus macrophages to follicular dendritic cells to B cells.
D) Passage of antigen from DCs that reside near HEVs to B cells.
E) All of the answers are possible.
Correct Answer:
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