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T-Cell Activation Requires Antigen Being Displayed in the Context of an APC

Question 15

Multiple Choice

T-cell activation requires antigen being displayed in the context of an APC and interaction between costimulatory molecules on the APC and the T cell.In addition to these two signals, T-cell activity is often influenced by cytokines.Which of the following is an example of how cytokines can influence T-cell activity in the presence of MHC presentation and costimulatory ligand interaction?


A) CD28 causes memory NK cells to be produced.
B) CD8 triggers apoptosis in T cells that recognize self-antigens.
C) IL-2 triggers T-cell proliferation.
D) Opsonins recruit eosinophils to present carbohydrate antibodies to naïve TC cells.
E) TNF- ? increases the production of IgM by activated T cells.

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