What is currently the BEST explanation for what determines whether a T cell develops into a CD8+ T cell or a CD4+ T cell?
A) CD4/TCR coengagement suppresses CD8 expression, and CD8/TCR coengagement suppresses CD4 expression.
B) T cells randomly downregulate CD4 or CD8, and only cells that still bind the appropriate MHC will get a strong enough signal to survive.
C) CD4 or CD8 expression is determined by the strength and duration of the TCR/MHC interaction.
D) CD4 or CD8 expression is predestined in the bone marrow.
E) Only ?? T cells express CD8.
Correct Answer:
Verified
Q13: MHCa mice that are irradiated and reconstituted
Q14: In negative selection, cells that receive _
Q15: What happens to autoreactive cells that escape
Q16: How do self-antigens that are specific to
Q17: Superantigens differ from regular peptide antigens because
Q19: Which of the following BEST describes the
Q20: Thymocytes whose TCR preferentially interacts with MHC
Q21: Which transcription factor is characteristic of TREG
Q22: TREGs have been shown to be protective
Q23: Which item listed below is NOT likely
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents