Deficiency in RAG1 and/or RAG2 can affect the proper development of which of the following cell types, resulting in decreased numbers of circulating cells of those types?

Question

Quizplus · Accepted Answer

Deficiency in RAG1 and/or RAG2 affects the V(D)J recombination process, which is crucial for the development of B cells and T cells, leading to decreased numbers of these cells in circulation. NK cells do not undergo V(D)J recombination, so their development is not directly affected by RAG deficiencies.

Deficiency in RAG1 And/or RAG2 Can Affect the Proper Development