Which transcription factor becomes translocated to the nucleus downstream of calmodulin activation?

Name: Which transcription factor becomes translocated to the nucleus downstream of calmodulin activation?
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Question

Quizplus · Accepted Answer

NFAT (Nuclear Factor of Activated T-cells) is the transcription factor that becomes translocated to the nucleus downstream of calmodulin activation. Calmodulin, upon calcium binding, activates the phosphatase calcineurin, which dephosphorylates NFAT, leading to its translocation into the nucleus.

Which Transcription Factor Becomes Translocated to the Nucleus Downstream of Calmodulin