Upon entering the thymus, thymocytes are classified as double _____ with regard to coreceptors; before exiting as single-positive, naïve T cells, they pass through a period in which they are double _____.

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Thymocytes initially enter the thymus as double-negative (lacking both CD4 and CD8 coreceptors). Through their development, they become double-positive (expressing both CD4 and CD8), before finally maturing into single-positive (either CD4+ or CD8+) T cells.

Upon Entering the Thymus, Thymocytes Are Classified as Double _____