Where did the most important attempt to end doctrinal disputes and clarify Christian orthodoxy take place in the mid-fifth century?

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The Council of Chalcedon, held in 451 AD, was a significant event in the history of Christianity as it aimed to resolve doctrinal disputes and clarify Christian orthodoxy, particularly concerning the nature of Christ. It is known for its definition of the two natures of Christ, divine and human, in one person.

Where Did the Most Important Attempt to End Doctrinal Disputes