How Did Outbreaks of the Plague Lead to the Founding

How did outbreaks of the plague lead to the founding of new universities in Europe?

A) Local princes received money and property from those who had perished, and they used this income to become patrons of education.
B) Mass death led many wealthy noblemen to lose faith in the church, and they opted to will their resources to secular institutions rather than to the church.
C) The plague forced more than 80 percent of existing universities to close their doors, necessitating the creation of new institutions.
D) Searching for the causes of the plague led to major scientific discoveries and the creation of new universities to train future scientists.