DNA or Nucleic Acid Vaccines Represent the Vaccines of the Future

DNA or nucleic acid vaccines represent the vaccines of the future because ____________. (Select all that apply)

A) they are highly effective against pathogens with low mutation rates
B) the complementary DNA created enters the nuclei of host cells and leads to both antibody and cell-mediated protection
C) they are administered with a gene gun into muscle tissues, eliminating the use of needles
D) they do not require refrigeration