Indicate the correct order of events leading to an Arthus reaction.
1) formation of immune complexes consisting of excess soluble antigen
2) lysosomal granules trigger an intense, localized response
3) damage to skin and accompanying blood vessels occurs
4) immune complexes settle out on the basement membrane of tissues
5) degranulation of neutrophils attempting to clear deposited immune complexes

Question

Quizplus · Accepted Answer

The correct sequence for an Arthus reaction starts with the formation of immune complexes (1), which then deposit on the basement membrane of tissues (4). Neutrophils attempt to clear these complexes and degranulate (5), releasing lysosomal granules that trigger a localized inflammatory response (2), ultimately leading to tissue damage (3).

Indicate the Correct Order of Events Leading to an Arthus