How do autoimmune diseases like rheumatoid arthritis, Type I diabetes and Multiple Sclerosis develop?
A) During maturation, negative selection fails to eliminate Class II MCH phagocytes with autoreactive receptors at checkpoint 1.
B) During maturation, negative selection fails to eliminate lymphocytes with autoreactive receptors at checkpoint 2.
C) There is an error during clonal expansion that generates an over-abundance of non-specific lymphocytes.
D) During clonal deletion, the TREG cells that suppress the development of autoimmune diseases are accidentally eliminated.
Correct Answer:
Verified
Q5: Which of the following antigens would be
Q6: Factors influencing antigen immunogenicity include all of
Q7: Which of the following statements about conjugate
Q8: B and T lymphocytes mature in the
Q9: Indicate the correct sequence of events in
Q11: During lymphocyte maturation, apoptosis occurs if an
Q12: Clonal selection and expansion involves _. (Select
Q13: Place the events of clonal selection and
Q14: Cytokines secreted by activated effector lymphocytes trigger
Q15: When clonal selection and expansion occurs in
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents