An active case of tuberculosis has to be treated with a multidrug approach. Which of the following list of antimycobacterial agents commonly prescribed is matched with its mechanism of action? (Select all that apply)

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Quizplus · Accepted Answer

Rifampicin inhibits RNA polymerase, which is crucial for bacterial RNA synthesis. Isoniazid inhibits the synthesis of mycolic acid, a key component of the mycobacterial cell wall, leading to cell death. Ethambutol also targets mycobacterial cell wall components but by inhibiting the synthesis of arabinogalactan, not mycolic acid directly. Pyrazinamide's mechanism is not accurately described; it is believed to disrupt mycobacterial cell membrane metabolism and energy production under acidic conditions, not by raising the pH to 10.

An Active Case of Tuberculosis Has to Be Treated with a Multidrug