These antiviral agents inhibit the RNA-dependent RNA polymerase and thus act as inhibitors of viral RNA synthesis. They are used for adults with chronic hepatitis C (any genotype) who do not have cirrhosis and have not previously received hepatitis C treatment.

Question

Quizplus · Accepted Answer

Sofosbuvir and velpatasvir are direct-acting antivirals that target the RNA-dependent RNA polymerase, inhibiting viral RNA synthesis, and are used in the treatment of chronic hepatitis C across all genotypes in adults without cirrhosis who are treatment-naive.

These Antiviral Agents Inhibit the RNA-Dependent RNA Polymerase and Thus