Nucleoside Analogs Inhibit Nucleic Acid Polymerization by ________

Nucleoside analogs inhibit nucleic acid polymerization by ________. (Select all that apply)

A) acting as terminators of synthesis after being incorporated into nucleic acid of host cell
B) having a structure where the 3' hydroxyl group on the sugar of the nucleoside or nucleotide is deleted or modified
C) after inclusion into growing DNA chain, the nucleotide analog blocks linkage of the next nucleotide
D) having a greater affinity for viral polymerases than for human ones thus producing selective toxicity at therapeutic concentrations