Which organ is involved in the first-pass effect after oral administration of a drug?

Name: Which organ is involved in the first-pass effect after oral administration of a drug?
Brand: Quizplus
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Question

Quizplus · Accepted Answer

On oral administration,drugs are absorbed and are carried via the portal circulation to the liver,where a percentage of the drug may be metabolized before entering the systemic circulation.After oral dosing,drugs reach the kidney,lungs,and spleen after passing through the liver.

Which Organ Is Involved in the First-Pass Effect After Oral