Which age-related change would affect transdermal drug absorption in geriatric patients the most?
A) Difficulty swallowing
B) Diminished kidney function
C) Changes in pigmentation
D) Altered circulatory status

Question

Quizplus · Accepted Answer

Altered circulatory status, common in older adults, can affect transdermal drug absorption by reducing blood flow to the skin and decreasing the rate at which the drug is delivered to systemic circulation. Difficulty swallowing (A) would not impact transdermal drug absorption. Diminished kidney function (B) would affect drug clearance, but not absorption through the skin. Changes in pigmentation (C) may alter the appearance of the skin, but would not directly affect drug absorption.

Which Age-Related Change Would Affect Transdermal Drug Absorption in Geriatric