The rhythmic depolarization and hyperpolarization of a lamprey's spinal column persists even in the presence of TTX. How does this support the central pattern generator hypothesis?

Question

Quizplus · Accepted Answer

The presence of TTX (tetrodotoxin) blocks sodium channels, preventing action potentials from occurring between neurons. The fact that rhythmic depolarization and hyperpolarization persist in the lamprey's spinal column despite this blockade supports the central pattern generator (CPG) hypothesis. This is because CPGs are neural networks that can produce rhythmic patterned outputs without sensory feedback, indicating that these patterns are generated internally within the network rather than being driven by external inputs or by action potentials traveling between neurons.

The Rhythmic Depolarization and Hyperpolarization of a Lamprey's Spinal Column