All of the Following Are Caveats to the Principles of the Canonical

All of the following are caveats to the principles of the canonical cortical circuit, except

A) thalamic inputs to the cortical circuit are not all sequentially ordered
B) the thickness of cortical layers is varied
C) inhibitory interneurons are numerous in the neocortex
D) there are multiple neurotransmitter types utilized by pyramidal neurons in the neocortex
E) some layers of the layered cortical circuit are very thin or missing altogether in the prefrontal cortex