During cross-bridge cycling, the molecule ______ binds to myosin heads, allowing the myosin heads to extend and bind to ______ filaments. ATP is hydrolyzed to ______ by the removal of inorganic phosphate. As hydrolysis occurs, the myosin head pulls against actin, and they slide relative to each other. The ________________ remain bound to actin until they encounter a molecule of ATP, at which point they release actin and extend to their original conformation (shape).
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