Sustained stress can lead to atrophy of the hippocampus, which in turn can contribute to:

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Sustained stress can indeed lead to atrophy of the hippocampus, a critical brain region involved in memory and emotional regulation. This atrophy can contribute to severe depression, as the hippocampus plays a role in regulating mood. It can also exacerbate conditions like Cushing's syndrome, where excessive cortisol levels can harm hippocampal neurons, and impair recovery or worsen outcomes after a stroke by affecting the brain's plasticity and recovery capabilities.

Sustained Stress Can Lead to Atrophy of the Hippocampus, Which