Mr Joel Daniels has been admitted to the ward with Pneumonia. He has a history of heart disease. The registered nurse who is working with you has asked you to work out the required volumes for the medications she is about to give him. The following three questions relate to his care.
-He is also to have the antibiotic ampicillin sodium 1.5 grams BD. Stock is 1 gram powder in 10 ml vial for reconstitution. The registered nurse asks you to calculate the volume of sterile water required, to reconstitute one, 1 gram vial to a concentration of 200 mg/ml if the powder displaces 0.7 ml when the solution is formed. The volume required for this task is

Question

Quizplus · Accepted Answer

To achieve a concentration of 200 mg/ml with 1 gram (1000 mg) of ampicillin, you need a total volume of 5 ml (1000 mg / 200 mg/ml = 5 ml). Since the powder displaces 0.7 ml, you subtract this from the total required volume to find out how much sterile water to add: 5 ml - 0.7 ml = 4.3 ml.

Mr Joel Daniels Has Been Admitted to the Ward with Pneumonia