Mr John Harris is a young man who has been admitted to the ward with severe Asthma and Pneumonia. On admission he has dyspnoea, is cyanotic and is using accessory muscles to breathe. His weight is 70 kg. Oxygen is commenced and an intravenous infusion established. You have been asked to care for him, with some guidance from the registered nurse.
-Mefoxin is available as 1 gram of powder in a 10 ml vial. Instructions accompanying the medication indicate that the 1 gram of powder will displace 0.5 ml on reconstitution. What volume of sterile fluid is required to reconstitute this medication to a concentration of 200 mg/ml?
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