Infections of mandibular premolars and anterior teeth spread into the sublingual space because the disease breaks out of the bone below the mylohyoid line.

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Infections in mandibular teeth tend to take a somewhat predictable course. Because the roots of the premolars and anterior teeth are located above the mylohyoid line, infection in these areas breaks out of the bone above the mylohyoid line and spreads to the spaces in the floor of the mouth, referred to as the sublingual space.

Infections of Mandibular Premolars and Anterior Teeth Spread into the Sublingual