Drosophila Larvae (Wt)showing Segmentation and Anterior-Posterior Axis

Drosophila larvae (wt) showing segmentation and anterior-posterior axis.
Refer to the image above to answer the following questions.
-When is a cell considered to be differentiated?

A) When it replicates by the process of mitosis.
B) When it loses connections to the surrounding cells.
C) When it produces proteins specific to a particular cell type.
D) When it appears to be different from the surrounding cells.
E) When it has transcribed all of its genes.