If the ob gene, which is responsible for the production of leptin, is down-regulated, the result would be

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Leptin is a hormone that signals to the brain to reduce appetite and increase energy expenditure. When the production of leptin is reduced due to down-regulation of the ob gene, the brain may not receive the signal to reduce appetite, resulting in an increased appetite. This can lead to an increased body mass.

If the Ob Gene, Which Is Responsible for the Production