Which of the following statements are fundamental to the clonal-selection theory of how the adaptive immune system functions?
I.Each lymphocyte has a unique membrane receptor that recognizes one antigen.
II.When the lymphocyte binds an antigen,it is activated and begins dividing to form many identical copies of itself.
III.Cloned lymphocytes have slight differences and are selected by the spleen for removal if they do not bind an antigen.
IV.Cloned cells descend from an activated lymphocyte and persist even after the pathogen is eliminated.

Question

Quizplus · Accepted Answer

All of the statements are fundamental to the clonal-selection theory of how the adaptive immune system functions. Statement I describes the concept of antigen specificity, statement II explains the expansion of the selected lymphocyte clones, and statement IV highlights the persistence of the cell clones. Statement III is also correct but not complete since the selection process occurs in the lymph nodes and not the spleen. Therefore, option C is the correct answer.

Which of the Following Statements Are Fundamental to the Clonal-Selection