Fever is caused by the release of pyrogens, such as cytokines and prostaglandins, which are produced by macrophages in response to infection or inflammation. These pyrogens act on the hypothalamus in the brain, raising the body's set point for temperature and inducing fever as the body tries to fight off the infection.

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What Causes Fever

Question 60

Multiple Choice

What causes fever?

A) Macrophages release pyrogens, which cause body temperature to increase.
B) Complementary proteins coat the surfaces of microbes and cause an increase in their temperature.
C) The activity of B cells and T cells causes the body to give off more heat.
D) Damaged cells release histamine, which increases body temperature.

Correct Answer: