You are a famous endocrinologist and are presented with a case in which a genetically determined male (XY) exhibits secondary female characteristics, including breast development and lack of facial hair growth. What may you hypothesize about this patient?

Question

Quizplus · Accepted Answer

Since the patient is identified as a genetically determined male with secondary female characteristics, one possible reason could be the lack of receptors for the male hormone testosterone. This condition is known as androgen insensitivity syndrome (AIS) which occurs due to mutations in the androgen receptor gene leading to partial or complete insensitivity to androgens, including testosterone.

You Are a Famous Endocrinologist and Are Presented with a Case